Dr. Sherajul I. Shelley: Development of this medical technology will play out in stages . the first will be replacement tissuses for diseases as Alzheimers parkinsons and diabetics , as well as new cartilage ,bone marrow and even new skin for burn victims. This tehnology is well under way and will put new tissues into bodies before the decade is out. By then , I reckon, transplant science will be capable of growing entire homogeneous organs, such as skin ad liver. In fact , the term transplant will be supplanted by the term tissue replacement .by the end of the next decade we will likely have entire complex organs available organ replacement. Until then ,true transplants will continue and broaden to include almost every organ in the body , except perhaps the brain itself.
The german school of psychology , gestalt hlds that in human experience , the whole is greater than the sum of the parts. In the not –too distant future , we may be exploring this in a physical sense as ultimately , we gain the ability to replace all our individual parts. If even our brains could one day be replaced , with a suoercomputer storing all our brains engrams which are then downloaded into the new brain , what is left that is truly us? Such a development might be the impetus for new branches of psychology and philosophy: what does it mean to be alive if there is no need for death?
Inorganic replacements will also progress as we learn more aout the functions of our bodies tissuses and organs. We already have devices and treatments for our special senses : for the eyes , we have glasses contacts control reshaping for the ears ,we have hearing aids and cochlear implants. Soon we will be implanting microsprocessors into faulty eyes and ears allowing the blind to see and the deaf to hear. We will also be producing artificial limbs that work very much like our own .by the year 2010 we will have a true six-million dollars man and that might well be the cost too.there are great problems facing the men health taking medicines alcohol injections but problems remain same for ED . men cant satisfy their women now we have penile implant and solved problems .in future scientist trying something more exciting to discover to solve erection problems .in 2015 there will be elixir of life for mens eections problems and reejaculte prostate cancer surgery able to birth baby now not.
Inorganic replacements will also progress as we learn more about the functions of our bodies tissuses and organs.we already have devices and treatments for special senses, for the eyes , we have glasses , contacts corneal reshaping for the ears we have hearing aids and cochlear implants .soon we will be implanting microprocessors into faulty eues and ears allowing the blinds to see and the deaf to hear. Erection for penile implant .we will also be producing artificial limbs that work very much like our own by the year 2015 we will have all handsome man and women.

However,late 2001 , a private company in worester Massachusetts called advanced cell technologies stunned the world when it created the first human clone. Although the embryo only grew to a microscopic ball of a few cells the experiments proved that human cloning is possible , and opened the doors for some much –needed scientific and ethical debate.
On july 31 , 2001 the US house of representative passed bipartisan legislation baning human cloning . the vote was 265 to 162, hardly a landslide.
What this suggests is that , even at the highest ranks of government , a lot of powerful people think human cloning is not a bad idea. Although I understand their rationale the potentiall to replace a lost child or create another Einstein or simply the freedom to expand human knowledge -I personaly think they are misguided. Human cloning is bad idea fraught with profound social and ethical implications . I figure that if we want to make more humans , do it the old fashioned way besides its farr more fun.
A company named geron has patents on six lines of stem cells ,but it also has somethings else in the works , geron is greek for oldman, suggesting exactly what this compny is investing aging.
The average human lifespan is now about 80 years in developed countries. That’s about how long an average set of genes will keep you going. Researchers at Harvard medical school recently conducted a genomic analysis of 137 100 year olds and found that they different from the general populations with respect to only about 10 genes found on chromosomes four. These genes it seems helped their carriers fight off many of the diseases related to aging heart diseases cancer dementia osteoporosis etc. one of the most encouraging conclusions one can draw from that research is that there are probably a few common mechanisms underlying those diseases.
One such mechanism seems to be an enzyme called telomerase, patented by geron. A telomere is like one of those plastic bits on the ends of shoelaces to keep them from unraveling caledd aglets for you trivia buffs it stops the chromosomes from unraveling and fraying at their ends. But telomerase prevents that from happening . the enzyme isnot contained in mature cells but is found in cancer cells. There it appears to contribute to the relative immortality of the cancer cells. In theory if we could introduce telomerase to normal mature cells or perhaps activate the gene that codes for it , we could achive immortality pone de leons fabled foiuntain of youth.


Although the study of telomerase will no doubt provide some interesting answers to our questions about the aging process , I don’t think we will be putting telomerase in the drinking water anytime soon. So far we understand far too little about how it works . we are. However discovering the role that many hormones play in aging. If we can create such hormone or control the aging hormone, probably we will solve aging problems and people will looks forever young.this heavenly change can be happen not means they will not die they will die definitely. In particular human growth hormone and dehydroepiandrosterone have been investigated with respect to changes in body compositions .evidence indicates that these and other hormones might help to show the aging processs by keeping our bodies stronger and healthier longer . combine this with improved methods of detecting preventing and treating diseases and its hard not to conclude that children born in the late 1909s can expect to live to see the 22nd century
Today a montreal company called nexia biotechnologies among a few others ,is combining the genes of two organisams to produce useful products. Although they don’t look quite as horrifying as the mythical greek creatures and to the best of my knowledge, havenot made any demands for youths or maidens these transgenic animals are similar in concept. For example , nexia has produced heards of transgenic goats and cows which have the genes for specific proteins from other organisams spliced into the genomes of their mammary glands .as results the milk they produce contains those proteinds it includes spider silk to make nexia’s structural products biosteel and its clot –busting protein tissue plasminogen activator . nexia has also entered into a joint venture with a european biotech to develop trangenic cows that will produce a host of therapeutic proteins.
I think this is a great idea and feel it will continue to evolve and progress. Why not take advantage of what mother nature has provided ; cute little protein factories ? you might think it cruel but in fact the goats are very healthy and happy and once you havest the sought after protein you can even use the milk more goat chese for everyone/ it seemslike a more cost effective way of producing therapeutic proteins than huge bioreactors full of nasty bacteria requiring considerable maintenance . with the goats ,once have inserted the gene , you just let them out into the back forty to graze. Their bodies are better designed to make proteins than any laboratory. We could ever hope to voncoct.
Among the most important changes we will see in future will be the information that the medical community will be ale to gather about patients and the way in which that data is analyzed . in that light biotechnology and information technologies will combine to provide physicians with broader and more profound knowledge about their patients .part of this will occur in the near term , as new imaging system allow doctors to peer ever more accurately inside the human body without the need for surgery. Three –dimensional holographic reproduction of a patients inner anatomy for example ,the brain will be used to plan and practice surgeries before the patients is admitted. During the procedure a huge array of sophisticated robotic tools will allow the surgen to conduct her work from outside the operating theater to limit possible contamination through a few tiny incision, the patients recovery time will be reduced to a few days or even hours.
Computer are now and will continue to be used for national drug design. This process employs computers in two ways by comparing the structure of proteins targets to known protein structures, it can be used to determine the molecular function of disease related proteins
Second by manipulating computer manifestations of proteins dugs can be computer –designed to bimd to specific structure and have a predetermined effect. Drug design can also be optimized by identifying and guiding the sunthesis of newr better therapeutic compounds.
Genomics and information technology are now combining as bioinformatics , allowing individuals genomes to be deciphered and compared to large genomic databanks. This will allow physicians to determine any exixting or predisposing genes that might cause problems and to address them before the problems arise. Medicine will shift from being reactive to proactive , focusing on preventing disease rather than treating it. Drugs will be tailor –made for the individual, by accounting for individual difference in absorption , metabolism and efficacy. Rather than using a hit or miss strategy for determining which drug works best for a patient. Physicians will be able to determine that answer inadvance and prescribe the single best drugs for that person. In drug traisls , a similar approach will be used to pre-screen potential candidates best suited for trial thius limiting costs and improving the quality of the data gathered. For some time now , Japanese scientist have been working on tiny, even microscopic machines that might be introducd into our bodies to deliver drugs to specific locations or accurately carve away atheroseclerotic plaques from our arteries . one day we might see entiter surgeries performed by intravenously introduced robot teams, which would be directed by physicians who never have to enter the body. These tiny machines would be conceived manufactured and directeddd by computers.
And lets not forget about DNA computers .scientist at lucent technologies have theorized that the particular electrical properties , structure and stability of DNA make it an excellent candidate for a semiconductor . david smith of thechnology futures , an Austin ,texas technology forecasting firm , was recently quoted as saying we could have DNA computer that matches the power of the human mind by 2020.
Furthermore , because of the smallness of DNA molecules microprocessors now the size of postage stamps could be shrunk to microscopic proportions . obviously this would mean that computers could be smaller, but would also provide an opportunity to use these bioprocessors inside the body as adjunct or replacement .our physiology could be monitored and output to medical databanks that would alert us, and our physicians of any medical problem that arises .some day we just might be able to add memory to our own brains and increase our computational ability.
Example that anthrax and ost count of how many headlines included that word. It has come symbolize a new frighting reality in human evolutions . for the first time, we are forced to contemplate the possibility that huge chunk of the populations might be wiped out by biterrosm. This is a nefarious and insidious form of war fare, potentially horrifying effective. And anthrax is only one many possible agents that could ne used to wreak havoc ao our society.
Although the method is new the outcome is not .humans have ,in the course of history. Endured many plagues , both bscterial and viral /in a sense our greatest enemy has been mother nature herself.
Many microbial threats exist in our environment. Its important to remember that whiles a few people have died . albeit tragically from exposure to the anthrax bacteria .more have died when agricultural runoff gets into municipal water supplies and as result e. coli bacteria infect hundreads. Remember, too that about 20,000 people die each year from the flu. Worldwide , 47 million people have been infected with HIV/AIDS, 21 million have died and another 36 million are still infected.
For years now I have been predicdicting that about one third of the worlds population will be wiped out by a contagious microbe within my lifetime. On my side is Stephen hawking who recently predicted that the entire human race would be eliminated by the end of this millennium. That seemingly morbid pessimism aises from the fact that mother nature is much strognger than we realize ,and we are not nearly as strong and clever as we think.everytime we humans think we have conqured an infectious disease , another nastier one appears.
Prime candidates as causes of the next global plagues are both viruses influenza and eboloa and now 2000 is covid 19. It is estimatedthat in the early part of this century and now about one third of all human were infected with a particularly deadly strain of influenza . twenty million people diedfrom it.the corona virusdied morethan one billion of people may be more still people will die nobody knows how many days this vaccine will work but still chance to due many people. This virus will be never be vanished it is still with us if immune system will weak the virus will will attack us again.this virus mutates with regularly and every few decades a very deadly strain arises .this will without doubt , happen again, in fact we are overdue for it.
Ebola by contrast has killed only a few hundread people in its half dozen or so outbreaks . what is frightening is the lethal power of the ebola virus the worst strain killed 90 percent of those far the only strain to kill human are passed by direct contact with the body fluids of the infected individual.and the virus kills within day.although horrifying that characteristic has actually saved us, because the virus is too hot. It kills its victims before it can be passed on to very many people and burns out quckly once contained.
My fear is that an airborne version of the deadiest stain will evolve and will have a slightly longer latency period . by exploting our capacity to travel rapidly around the glove .the virus could easily infect billions of individuals within a few months.
Biotechnology can certainly help us here. Many biotechs are working on new antibiotics for bacterial infections , they are seeking antiviral products for disesase such as HIV/AIDS influenza even ebola even covid-19 . because microbial diseases mutate and evolve so quckly finding cures for them is like shooting at a moving target. Biotech are also investigating methods to boost our own natural defense system .a combinayion of those two biotech thrust will likely make infectious diseass less of global threat than it is now but I doubt we will ever win that war pnce and for all.
In solving problemswe should have strong leadership in the world.all world leadership has failed to solve all worldy problems ,we need hardworkers true I want to mentions lot of countries have bioterrosiams and bacterial weapon besides other chemical and other weapons to kill humanbeings for theireown countries and economic intentions.actually chiana wants to create such virus or bacterial weapons and thus they tried to create corona virus in theire own laboratory. President trum is a patoritic president for USA. He tried hard for his own life to brings economic welfare to USA and he did it. He is right this is not covid-19 this is chaina -19 who destroy lot of he said this is not covid but it is chiana -19.chaina wants capture whole world by there bioterrorizam through covid-19.lot of immigrant intellectual peole inside USA living with hardship and serving USA without looking them USA brings lot of refuses without skills paying lot of money fo them without reasons president trum said please make America great but not to brings and giving welfare without reasons.make first USA great then you tthink to whom you will give immigrations.anyway this is politics not to politices country but to make great country and it will solve the all problems invest money where you need but not to invest were nothing will brings and will brings lot of sufferings.

A new study suggests that former President Donald Trump’s inflammatory rhetoric around the coronavirus, which is believed to have originated in China, helped spark anti-Asian Twitter content and “likely perpetuated racist attitudes.”
The Asian American community has experienced a striking rise in incidents of hate since the onset of COVID-19, according to officials and advocates, and critics say the former president’s repeated use of “China Virus” and other terms helped fuel an environment of hatred.

“Anti-Asian sentiment depicted in the tweets containing the term ‘Chinese Virus’ likely perpetuated racist attitudes and parallels the anti-Asian hate crimes that have occurred since,” said Dr. Yulin Hswen, an assistant professor of epidemiology at UC, San Francisco and the study’s lead author.
The results, published in the American Journal of Public Health, come in the wake of a string of attacks on Asian communities in the U.S., including a series of shootings in Georgia that left six women of Asian descent dead.
The study indicated a difference in anti-Asian sentiment when using neutral hashtags such as #COVID-19 versus racist hashtags like #Chinesevirus — 20% of the hashtags associated with #COVID-19 demonstrated anti-Asian sentiment, compared to 50% of hashtags with #Chinesevirus.

former President Donald Trump addresses the Conservative Political Action
Dr. John Brownstein, an ABC News Medical Unit contributor and author of the study, said that such online conversations can spark violent reactions.
“We often see that online conversations that contain messages of hate don’t stay online,” Brownstein said. “Oftentimes, the conversations that take place on social media results in real world consequences.”
Dr. Daniel Rogers, an expert on misinformation at New York University, said that hateful content on social media can lead to more of the same being served up to users via platforms’ algorithms.
“As platform algorithms pick up on engagement around this toxic content, they recommend increasingly more extreme content to users until their feeds are dominated by nothing but the most extreme stuff, goading those users with a propensity toward violence to potentially committing hate crimes,” Rogers said.
Researchers also found that the timing of the former president’s tweet was significant. The first time he used “ChineseVirus” was March 16, 2020, and the following week saw an increase in anti-Asian hashtags and a rise in hate crimes.
International health officials purposely avoided attaching geography to the virus, as had been done in the past, to avoid casting blame, but Trump insisted on tying China to COVID-19 at every turn.
Experts and policy makers warned against using inflammatory and racist tweets since they can serve as a rallying cry for hate crimes.
“Don’t attach locations or ethnicity to the disease, this is not a ‘Wuhan Virus,’ ‘Chinese Virus’ or ‘Asian Virus,” the World Health Organization wrote in a February 2020 bulletin.
In a wide-ranging press briefing on Wednesday, Biden administration press secretary Jen Psaki said that damaging rhetoric from the prior administration led to “inaccurate, unfair” perceptions that threatened Asian Americans.
One year ago, at the start of the pandemic, Trump condemned xenophobic attacks against Asian Americans, but he continued to use incendiary rhetoric and deny doing so was racist.
On the night several Asian women were shot dead in Atlanta, he referred to COVID-19 as the “China Virus” on Fox News.
The Trump Organization did not immediately respond to a request for comment from ABC News.
Hswen said it’s more important now than ever for our leaders to use neutral language because inflammatory words can influence people’s behavior toward particular groups.
The study results, Hswen said, “confirm that nationality, race, or ethnicity should not be attached to disease nomenclature, as these names can carry pejorative connotations that can stigmatize these communities.”
Anyway certainly many ethical issuses surrounded the commercialization of biotechnology . I could wax poetic for many works on this topic but that is not the purpose of this work.
However , some ethical isuses also have both commercial and global implications.
I am fascinated and amazed by what biotech has achived in a very short time. Soon diseasewill become more of an iconvenience than a threat to our survival. The problems is that , initially at least these technologies are enormously expensive . as noted earlier in this work .
Economics of scale will lower costs overtime as biotechs ramp up their production but that will bee a slow , steadly process . meanwhile how do we best make use of biotech products to ensure they benefit humanity.?

Here I like to mentione one Bangladesh eminat Islamic scholar named ALLAMA MUFTI HAFEZ MOULANA IBRAHIM
The pathways of history, the people of Bangladesh have gone through natural disasters, political turmoil, and man-made catastrophes. In response, they have fought, resisted and survived using their resourcefulness. Traditional cultures in Bangladesh have always been used as a way to increase spiritual and mental strength, as well as nourish the resourcefulness needed to face problems in everyday life such as covid -19. Mufti Ibrahim warn and request follow up quaranic sciences and Muhammad SWS prophesphys medicines you would be safe from corona virus.

said when corona appears that more millions people will die in world and specially he mentioned amoung the worlds population ,more INDIAN people will die more for covid -19.and it was happened last march april 2021.and his prophesy was fulfilled but worned INDIA be careful but nobody belives him but alas it was happened.and it is true that Bangladeshi primeminister follow the rules and Bangladesh was safe thufg Bangladesh is neigbouring country INDIA.
Honestly speaking ampung my neigbour hood and also people from Bangladesh ,Russia, Pakistan and india lot of people knows me as a microbiologist virologist and immunologist when corona pandemic rok out they asked me dr. shelley what we can please advice us:
I ty to advice them maintain cleanlessness if affected please mind more cleanness washing clothes use new cloth when you are outside and clean your body with warm water and clean your body with white towels and drink hot warm wateror lemon or orange juice and give air to your nose with hair dyier and take warm water vapor
And drink moring 5 ml olive oil and then after breakfast take black seed oil 5 ml and evening take 5ml coccount oil . and make paste with muster oil leaves Padina leaves making paste with master oil and eat with bashmati rice or kalizira rice. Eat 3 times a day .
Before sleep drink a cup of milk with pure honey .this is prophetic medicines and eat green pumkin curry with green chilly.
Peole listen to me and recover from covid and said thanks to me.many people by this traditional ancient biotechnology also can make such a syrup with applying modern sciences.
Belive me lot of people saved by doing that still people taking my advices.and I publishe this thing in evening Bangladesh news paper named: experimental value and aseptic technique articles beginning of the year.

It is true that prime minister hasina is the mirror , creating Bangladesh is Golden Bengal.she is the only rightest priminister and true leader for the Bengali nations.
However whatever and how it happened but now we need to increase our biotechnology research to STOP Any pandemic that is going to attack we have to think about the following 3 doctorine.all people can be united under this following banner problems will be solved
If you belivers you will never be bad persons brings belive in rerigion your hear will be clean and the body will be safe from any diseases and but we have to research to invention a new method following biotechnology and discover new drugs and methods. And world leadership should be perfect and true and actionable to their responsibilities.
If GOD will close the door of miracle(HEKMOT) but sure HE will open the door kindness and forgiveness(RAHMAT)
GOD gives us knowledge and brain by using is through technology we can solve thousands of problems.
Anyway,the governments or health plans of most wealthy countries now pay many biotech products but costs typically run in the tens of thousands of dollars per year. How long can this go on. Eventually each of us will probably benefit from one or more biotech products , so who is going to foot the bill. My sense is that ,over time , biotech products and services will actually save society a great deal of money by preventing disease and reducing the need for hospitalization . in the meanrime , only wealthy countries will have access to most of its products.
But what about the third world? Already in some African countries, HIV/AIDS infected about one third of the population. The drug cocktail that keeps sufferes alive here is far too expensive research is over, we could ,if we had the social and political will, provide the medication to everyone. The problem is that if we did , dug companies would be out of business very quickly .the question then becomes . is there a public will to provide drug at price that reflects only the cost of for people there to afford. As already mentioned , much of that cost is eailized during drug development the cost of production itself is often a few cents per pill. We currently extend legal patent and pice protection to dug compaies sothey can recoup their development costs and realize a profit but once the rsearch is over we could if we had the social and political will, provide the medication to everyone. The problem is that if we did drug companies would be out of business very quickly . the question then becomes , is there a public will to provide drugs at a price that reflects only the cost of production to developing nations, while charging our own citizens full freight? Whaat would stop the unscrupulous from simply buying the drugs abroad and resellings them here? I must confess I don’t forceses an easy solution to these problems .but in the end we should do whats best for the most people over the long term.
The way we think about drugs will change in the coming decades . very soon instead of getting a flue shot by needele , we might have the vaccine blasted into our system by a non iinvassive jet mechanism about the size of a lipstick container . after all. Sticking sharp metal objects into your body is not such a good idea . each year in north America , there are 600000 to 800,000 injections related accident ,resulting in litigation costs totaling hundread of millions of dollars . also , while injections are good at introducuing drugs into circulations they are not particularly good at maintaining the desired effect over a long period of time. Anyone who has been to the dentist has a good fell for this –pun the future we will see increasing use of inhalers , especially to deliver gene therapies . today’s orally imgested capsules and tablets are limited in effectiveness by absorption and metabolisam and can cause digestive problems and other side effects . orally ingested capsules will still used for some time , but increasingly these will contain large organic compounds that are asorved from our digestive tracts in tiny fat droplets.some drugs will be introduced into the system more slowly and evenly using patch technologies similar to todays nicotine patces . many drugs . including vaccines ,will actually be produced in common foods such as bananas and potatoes . I call these pharmafoods instead of taking a pill everyday, you would eat a speciall banana once a week and it would taste the same as always. We are already seeing calcium enhanced and vitamin enhanced orange juice . that is just beginning.
The future looks extremely positive ideed for the biotech sector / already at the time of writing just a few months after the events of september11 as they have become universally known the biotech index sits at 811 , some 19 percent above its low of 681 on September 19 two days after the markets reopened . as I have said many times in public and private biotech will lead the way out of the bear market , sometimes that has already stayed. If yu follow the strategies set out in this work the next five or so years should be very profitable for you and me too. Society wins as well , since our financial success is predicted on finding cures for diseases.
I wish I could assure you that everythings will be coming up roses but that would be mialeadings.
We will also witness , I asure you turbulent times .as the markets rebound trillions of dollars will begain to pour out of fixed –income investments and back into the markets. This is simply a matter of personal and institutional wealth and the size of the economy. First , remember that the bond markets hold ,on average about ten times the capital invested in stocks. Bond markets do well with falling interest rates. I know this seems country, but think of it this way , would you want to buy a new bond at two percent, or a bond someone else has been holding that pays five percent bonds are commodities like any other and as interest rates fall , those held from past investment that pay more become more valuable . of course the opposites is true too. As interest rates rise ,new bonds become more attractive . so old ones are sold off. At tha same time , stocks usually rise due to the favorable investment climate and the increase money supply brought on by low interest rates. Interest raytes fell 11 times in the year and at a 40 year low of 1.75 percent , they cant fall much frther . the only way out is up.
What all this means is that ,in the near ftre , money will pour back into the stock markets as the broader economic pictre improves . this will provide pward pressre on biotech share pricess and open the window for new financing . biotech will grow bt alas I fear it will at a rate too high to sustain. Psychology plays a large in investment and markets are self –corecting ,not efficient . I say this with confidence given that the 2001 nobel prize in economics went to two economics who are of like mind on this issue . therefore ,like a swing set in motion , the biotech sector will experience a number of boom and bst cycles with diminishing highs and lows , although the overall long term trend will definitely be up. Eah time a major breakthrough hits the media , hungry investors will bite at anythings that looks hot.
Now I like to say somethings alse .see Bangladesh as a example .the state secretary USA dr. henerry kisinger said looking at the csituation of poverty in Bangladesh in 1971 said Bangladesh is is the bootmless basket but now you see at Bangladesh is in some comparable with Europe and other developed country is the most developing even some extend even better than developed happended not due to time but the efforts of Bangladesh peoples and and the government government of prime minister sheikh hasina .in 1971 babgladesh cant produce even pain killers but now bangladsh producing large number of varieties drugs medicines is quality is keeping up even USA.

See Bangladesh garment industry one is most famous industry in the world .all over the world has great demands.crime hatret everythings is under control of government making savior punishment rules to control thieves robbery and rapes and killings .and beautification Bangladesh is going on villages and cities using electirification and digital Bangladesh. Even government controlling red light districtic women and children ,making the special areas to live and controlling them to giving them job offers. No description on Hzra women and prostitute women special places and controlling them with sanitary hygienic condion and creating for them work.taking care their elderly men and women and children and suffering peoples . creating villages with making high land to save them from flood.taking care of rivers creating good roads both sides of the rivers.everyday new houses is going to blid to give people proper shelter .agricltre sector developing to grow more crops and foods fruits and vegetables usining biotechnology cattles and animal sciences are developing. Babgladesh GDP is higher than even INDIA and Pakistan and it is comparable with developed care are under care of governments lot of government and private health care system are developed .studies and research are going up day by day. Now women education is hire than any other country. Most of women are highly educated than men.and getting gold medals due to exvelence studies. Most of Bangladeshi and now orking in outside the country with the prestize positions and became famous lot of Bangladeshi people working hard in aboad and bringing lot of remittance for Bangladesh.

inpeace in this year.
But mainly we need to discover new drugs for solving disease problems in human being through the using biotechnology we have already seen this happen as a result of the anthrax scares. Biotechs that research or make anythings to do with pathogens diseases causing microbes have jumped significantlywe know Cepheid which makes equipment for genetic analysis of pathogens ,up 131 percent bioreliance a maker of smallpox vaccine up 129 percent nanogen which has a contract from the USA army to develop chips that detect biwarefare pathogens up 92 percent all within five weeks of September 11.
All that looks like great news for investors and if they were savvy enough to get in on September 17and sell today , they have reason to gloat. But it makes me nervous . it tells me that many traders are wiliing to jump into the markets ahead of the investors , looking for so called easy money. If a companys shares rise 131percent in five weeks , how likely is it that such explosive growth will continue ? if it continued for 12 months , cepheidwould grow from a 300 million dollars company to about a 300 billion dollars company in a year making it one of the worlds largest . as George bush sr. would say not gunna happen .what will more likely happen is a precipitous drops in price and you sure don’t want to be buying just before that occurs .today only four days after Cepheid hits 52 week high of 11.48 accounting for the 131 percent noted above ,it traded as low as 6.70 , a 42 percent loss if you were the poor sap who bought in at 11.4 dollars.
Traders like that kind of volatility , especially furthers traders . but if you are , as I trust you are an investors , times like that can be unnerving indeed.
As much as rash of drugs approvals might send biotechs storming up. A rash of bad news will send them right back down again with equal velocity . like roller-coaster lovers , you need a strong stomach . eventually , as the sector matures further . these precipitios hights and lows will even out like the ever diminishing rings that extend from a rock thrown into a pond.calmer heads and smother times will prevail.
My recommendations for investors is to avoid over –managing or over analyzing . buy in, make reguar contributions and sell if and when the time is right . keep a careful eye on things, but whatever you do , don’t panic . no stock price goes straightup forever. If there is a precipitous rise and ypu own shares , sell. You win.
Bad things happen . sometimes they are bad things on a massive scale, such as the events of September 111 , or the 1995 earthquake in kob , japan , which killed 5000 and in part triggered the asian economic meltdown.sometimes they are on a smaller scale , such as failed clinical trial , an economic sowdown or the failure of a business plan. What is important is that we keep a reasonable perspective . expert the best, but prepare for the worst. Sad to say , history shows there will always be more wars , more deaths , more tragedy but in the long run things are never quite so bad as they seem at th time. There are no sure things in life. For example , I am going to a hockey game tonight with to watch my favorite teamthe .or to watch cricket . someone might fly a plane into general motors place or put anthrax or corona virus into the ventilation system but the odds are pretty good that they wont am I concered?
A tiny bit , I confess . will it stop me from going to the game not a chance if I don’t go the terrorist win life must go on Go said biotechnologist David.

If primeminister Hasina want to make Golden she should go through biotechnologist and ordered her countries pharmaceuticals company to invest in biotechnology.ther is key to make Bangladesh to golden bengal dreams of Bengali father of the nation bangobhandu sheikh mujibur rahman.

Now about agricltral biotechnology :
Ther were , 15 proposal my proposal was top of the list ,it brings lot of signicanse in the al the projects. There were my name is the top of the list please see the book and edited by me,TO ATTEND THAT WORKS AMOUNG ALL SOVIET SCIENTIST I WAS SELECTED TO JOUN THAT WORKSHOP
I worked amoung with above mentioned scientist .all were distinguished scientist it was pleasure to work with them in theaae field e together developed biological nitrogen fixation and it brings lot of significances in agricultural biotechnology.
Key points:
1. The united nations university is organizing a workshop on nitrogen fixation in thee rhizosphere of rice which will be co –sponsored and hosted by the international rice esaerch institute , ls banos , Philippines 28 april -4 may 1984 . the overall aim of this worshop is to established a neork of institutions cooperating in this fiel of research
2. The purpose of this letter invitation to invite me dr. shelley to participate in the workshop. First . let me dr. Robert kokke senior program officer development division .in the scope of its commitment to strengthen the biotechnology research capacity of institutions in developing countries , the UN university is working to establish a co-ordinate research projects on nitrogen fixation in the rizosphere of rice still that work going on and implemented IRRI and brings lot of economic welfare to the developing country.
3. As know it is well –known that rice is thee stable food of three –fifths of the world populations and that high nitrogen inputs are required for good yields.part or possible all of this nitrogen requirement may eventually be met through biological fixation of nitrogen from the atmosphere. Researchers at the Japanese national institute of geneics under the leadership of Dr. Y ukinori Hirota have found some ricee strains which haveee a capacity to use nitrogen fixed by microorganisams living in the rhisosphere . they are now attemting to transfer this capacity oto high –yoelding cultivars.and Former USSR Dr. sil shelley and profeeesor DR OF SCIENCES V.T EMTSEV FOUND ANAerobic acteria genus clostridium to fix atmosapheric nitorogen see his articles and dr. shelley was invited in same year to attended to Bangladesh crop response correlations studies and his research work anaerobic nitrogen fixing bacteria genus clostridium was very much acceptable and his suggestions was accepted publishe in news paper Bangladesh observer and paper was published in book .in conference proceddings in first pages crop response correlations studies pleae see attached documents.the approach is multi disciplinary , involving molecular biologies , plan breeders soil scientists and others.
4. It is happy to say .the UN university has chosen to work on biological nitrogen fixation for several reasons. The research will be ofimmediate importance to developing countries. The results of this research are more readily available since it is carried out primarily in institutions rather than industrial laboratories . by catalyzing a greater interest in this field in developing countries the UN Universities hopes to create core groups of researchers which will then have the capacity to deal with other topics in the field of biotechnology.
5. A modest amount of the UN University funding has been allocated to this project for research support, fellowship award and communication of results .dr. Hrota is very co –operative and willing to ecive a nuber of post graduate or post doctoral scientists from developing countriesto work with him in his laboratories. Other advanced laboratories where scholars can participate in the research are invited to do the same. The visiting scholars should spend a period of six to twelve months in the host institutions.the host institutions are entitle to receive a compensation for their costs. More experienced scientists from developing countries may be supported t make scientific visits of one week to three months to other laboratories participating in the program. Consultants may also be hired fot specific missions small sums of money may be used to strengthen research in certain individual discissed by the participants . as a participant we performed all task and implemented to the developing country still today there are lot of crop response.
6. Dr. Robert recognizing my expertise and expeience in this field and dr. rober rober kokke said to me he would like to invite meed me in several workshop to discussed with him about the nitrogen fixing bacteria to participate in this and various workshops or to propose a qualified substitute if I dr. shelley cant not atten but I attended in netrland UK FINLAND ETC. and that will be a highly technical worship comprising esearchers working in this field a ist of the specific meetings objectives and provisional agends are enclosed the major activity will be discussions on the states of current research as perceived by the individuals participants and ideas for further cooperative efforsts.
7. i immediatel response with my research works and proposal see on the first my name dr. s.i.shelley dr,robert kokke would like to solicit a my proposal on some aspects of the topic that my feel to be of immediate importance the enclosed projects proposal form outlines the information that should be included .[roposal shuld prefeably be submitted in advance until 1 15 april 1984 ,they should be sent to dr. robert kokke in tokyo . thereafter they should go to dr. i watanae at irri , po box 933 manila philippines and it was done by me dr. si.shelley
8. please see to attend the different meeting the una universty wil provide economy class round trip tickets from my academy institutes to los banos plus per diem for the days of the conference to be paid according to the un standard. and i confired and work out.EXPLAINED BY DR. ROBERT KOKKE.
10. After successfully projects completions sent me edited version of the recommandations of the UNU –IRRI workshops on nitrogen fixation in therizosphere ofrice held at IRRI , LOS BANOS , 28TH APRIL 3 MAY 1984
11. DR. ROBERT KOKKE wishes also to take this opportunity totanks me for participating in the workshop and for the valuable contribution which I made to it. And he hoped the workshop will be the beginning of fruitful co-operation of scientists in this areas
12. My suggestions and he mentioned in his letter I dr. shelley wishes me to to revise or ewrite my proposal to unu in the light of thr discussions and the ecommandations of the work and see please his appreciation letter and evetually i reedited andsubmitted to him .pleasesee enclosed book.
To have alternatives to intensive use of nitrogen fertilizers in the cultivation of rice ., it is necessary to explore the potential of biological nitrogen fixation in rice fields. Among the known system , rihizospheric nitrogen fixation has ben relatively underexploted. In view of this , the participants have agreed to recommend the establishements of a network of research in this aeaaas under the UNU program .aftr reviewing the current state of knowledge , it is fet that more fundamental research is needed before investing large amounts of money in field experiments the following aspects have been identified in which in depth studies are essential to have a clear picture of plant –bacteria associations:
1.survey of diverse rhizosphere ecosystems of rice for isolating and identifying

I.Active colonizers and
II. Aactive nitorogen fixers.
Remarks my anaerobic bacteria considers active nitrogen fixers
2. accurate and reproducible assessment of nitrogen fixation and colonization potential different isolates.
I made reoomendation and we together took following declaration.
i. To have alternative to intensive use nitrogen fertilizers in the cultivation of rice, it is necessary to explore the potential of biological nitrogen fixation in rice fields .among the known systems, rizosphereic nitrogen fixation has been elatvely underexplored. In view of this , the participants have agreed to recommend the establishmen of a network of research in this area under the UNU program
ii. Note: after reviewing the current state of knowledge , it is felt that more fundamental research is needed before investing large amounts of money in field experiments. The following aspects have been dentified in which in depth studies are essential to have clear picture of plant bacteria associations:
iii. A.}survey of diverse HIOSPERE of rice for isolating ad identifying
iv. clonozers and ii active nitrogen fixers.

1. Accurate and reproducible assessment of nitrogen fixation and colonization potential of different isolates.
2. Accurate and reproducible assessment of the ability of rice cultivativars to benefit from biological nitrogen fixation.
3. The meeting also recognized the necessity to increase the capability of young scientists from developing countries to apply molecular biological techniques to rhizosphere BNF through training in recognized centers,
In this areas the meeting has stressed the necessity of adopting the following uniform methodologies to aarive at meaningful comparisions of the results from different laboratories.

• Isolations of strains
• The staring materials must be obtained from an actively fixing plant, as proven by aceetyline reduction and must include roots as well as adhering soil.
• Only very abundant bacteria are worth isolating as they are likely to be good colonizers.
• Dilutions of the starting materials can be inoculated to diverse media, including spermosphere models.
• Among underinvestigated groups of nitrogen fixing bacteria are mehane using bacteria , cellulolytic bacteria , hemicellulolytic bacteersa and actinomycetes.
• A great effort must be made to determine isolates using proper available methodologies.
1. Assessment of strain potential
2. It seems important to distinguish the potential for nitrogen fixation and the potential for colonization.
3. The potential for nitrogen fixation can be assessed using monoaxenic systems such as the spermosphere model.
4. Models closer to natural situations will be preferred if they show an atleast similar comparable reproducibility.
5. Reference strain common to all participants shall be included in such comparative studies for enterobacteriaceae it will be klebsiella oxytoca NG13 –NIF + , NIF _ pfr.
6. Hirotha and for azospirillum it will be A. lipoferum 34H from phr.
7. Watanabe.
8. Regarding the potential for colonization available methods counts, lectin rection , attachments measurements and microscopic observation must be evaluated and standardized before becoming routine methods.

• Assessment of rice cultivator potential
• Here again the spermosphere model can be used as simple routine procedure as long as allowance is made for difference in the size seeds. Whenever possible results must be confirmed by experiments on older plants using 15 nitrogen , this can be made by comparing cultivars to reference cultivars on the basis of their 15 nitrogen content either with uniformly labeled soil or using natural aboundance of 15 nitrogen if a soil is available with a hgh vaue.

Reference rice proposed are : oryza japonicaT65, cycle duration 110 days , oryza sativa IR58 , cycle duration 100 days m, oryza sativa IR42, cycle duration 120 days.
Detecting inactive lines seems as important as detecting very active ones . the former can become useful controls in further experiments.
In addition to rhizosphere biological nitrogen fixation , the meeting recognized the potential role of other process vesicular –arbuscular endomycorrhizae , growth promoting substances , other nitrogen fixing systems in relations to rice production which are beyond the scope of the proposed network.


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